Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.
Genome-wide association studies (GWAS) have mapped risk alleles for at least 10 distinct cancers to a small region of 63 000 bp on chromosome 5p15.33. This region harbors the TERT and CLPTM1L genes; the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play...
Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2014
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