Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.

Genome-wide association studies (GWAS) have mapped risk alleles for at least 10 distinct cancers to a small region of 63 000 bp on chromosome 5p15.33. This region harbors the TERT and CLPTM1L genes; the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play...

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Bibliographic Details
Main Authors: Wang, Z, Zhu, B, Zhang, M, Parikh, H, Jia, J, Chung, C, Sampson, J, Hoskins, J, Hutchinson, A, Burdette, L, Ibrahim, A, Hautman, C, Raj, P, Abnet, C, Adjei, A, Ahlbom, A, Albanes, D, Allen, N, Ambrosone, C, Aldrich, M, Amiano, P, Amos, C, Andersson, U, Andriole, G, Andrulis, I
Format: Journal article
Language:English
Published: 2014