Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

CD4+ T cells are central mediators of autoimmune pathology; however, the definition of their key effector functions in specific autoimmune diseases remains limited. Pathogenic CD4+ T cells within affected tissues may be identified by expression of markers of recent activation1. We applied this appro...

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Bibliographic Details
Main Authors: Rao, DA, Gurish, MF, Marshall, JL, Slowikowski, K, Fonseka, CY, Liu, Y, Donlin, LT, Henderson, LA, Wei, K, Mizoguchi, F, Teslovich, NC, Weinblatt, ME, Massarotti, EM, Coblyn, JS, Helfgott, SM, Lee, YC, Todd, DJ, Bykerk, VP, Goodman, SM, Pernis, AB, Ivashkiv, LB, Karlson, EW, Nigrovic, PA, Filer, A, Buckley, CD, Lederer, JA, Raychaudhuri, S, Brenner, MB
Format: Journal article
Published: Nature Publishing Group 2017