Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila

Non-genetic information can be inherited across generations in a process known as transgenerational epigenetic inheritance (TEI). In Drosophila, hemizygosity of the Fab-7 regulatory element triggers inheritance of the histone mark H3K27me3 at a homologous locus on another chromosome, resulting in he...

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Bibliographic Details
Main Authors: Fitz-James, MH, Sabarís, G, Sarkies, P, Bantignies, F, Cavalli, G
Format: Journal article
Language:English
Published: Cell Press 2024