Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase.
The X-ray crystal structure of Mycobacterium tuberculosis shikimate kinase (SK) with bound shikimate and adenosine diphosphate (ADP) has been determined to a resolution of 2.15 A. The binding of shikimate in a shikimate kinase crystal structure has not previously been reported. The substrate binds i...
Hlavní autoři: | Dhaliwal, B, Nichols, C, Ren, J, Lockyer, M, Charles, I, Hawkins, A, Stammers, D |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2004
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