Four types of Ca2+ signals in naive CD8+ cytotoxic T cells after stimulation with T cell agonists, partial agonists and antagonists.

Stimulation of T cells via the T cell receptor (TCR) leads to an increase intracellular in free Ca2+ levels ([Ca2+]i) and the activation of the MAP kinase signaling pathway. This study analyzes for the first time Ca2+ fluxes in naive cytotoxic T cells stimulated with full agonists, partial agonists,...

Descrizione completa

Dettagli Bibliografici
Autori principali: Bachmann, M, Mariathasan, S, Bouchard, D, Speiser, D, Ohashi, P
Natura: Journal article
Lingua:English
Pubblicazione: 1997