Tight coupling of astrocyte pH dynamics to epileptiform activity revealed by genetically-encoded pH sensors

Astrocytes can both sense and shape the evolution of neuronal network activity and are known to possess unique ion regulatory mechanisms. Here we explore the relationship between astrocytic intracellular pH dynamics and the synchronous network activity that occurs during seizure-like activity. By co...

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Bibliographic Details
Main Authors: Akerman, C, Raimondo, J, Tomes, H, Irkle, A, Kay, L, Kellaway, L, Markram, H, Miller, R
Format: Journal article
Published: Society for Neuroscience 2016