Calmodulin dissociation mediates desensitization of the cADPR-induced Ca2+ release mechanism.
Ryanodine receptor (RyR) activation by cyclic ADP-ribose (cADPR) is followed by homologous desensitization. Though poorly understood, this "switching off" process has provided a key experimental tool for determining the pathway through which cADPR mediates Ca(2+) release. Moreover, desensi...
Huvudupphovsmän: | , , , , |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
2002
|