Calmodulin dissociation mediates desensitization of the cADPR-induced Ca2+ release mechanism.
Ryanodine receptor (RyR) activation by cyclic ADP-ribose (cADPR) is followed by homologous desensitization. Though poorly understood, this "switching off" process has provided a key experimental tool for determining the pathway through which cADPR mediates Ca(2+) release. Moreover, desensi...
| المؤلفون الرئيسيون: | , , , , |
|---|---|
| التنسيق: | Journal article |
| اللغة: | English |
| منشور في: |
2002
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