Calmodulin dissociation mediates desensitization of the cADPR-induced Ca2+ release mechanism.

Calmodulin dissociation mediates desensitization of the cADPR-induced Ca2+ release mechanism.

Ryanodine receptor (RyR) activation by cyclic ADP-ribose (cADPR) is followed by homologous desensitization. Though poorly understood, this "switching off" process has provided a key experimental tool for determining the pathway through which cADPR mediates Ca(2+) release. Moreover, desensi...

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Detalles Bibliográficos
Main Authors:	Thomas, J, Summerhill, R, Fruen, B, Churchill, G, Galione, A
Formato:	Journal article
Idioma:	English
Publicado:	2002

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