Novel models of late onset, progressive osteoarthritis caused by point mutations in the two alpha chains of collagen type I

Genetic modification is a useful tool for identifying novel genes associated with osteoarthritis (OA) and we have combined a phenotype-driven screen with ageing to identify mutations resulting in late-onset or age-related disease. As part of the Harwell Ageing Screen mutagenised mice were aged to 18...

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Bibliographic Details
Main Authors:	Blease, A, Wisby, L, Haynes, A, Nicol, T, Falcone, S, Lad, H, Esapa, C, Horwood, N, Thorpe, C, Thakker, R, Screen, H, Vincent, T, Browny, S, Potter, P
Format:	Conference item
Published:	Elsevier 2017

Novel models of late onset, progressive osteoarthritis caused by point mutations in the two alpha chains of collagen type I

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