Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16.

CDK16 (also known as PCTAIRE1 or PCTK1) is an atypical member of the cyclin-dependent kinase (CDK) family that has emerged as a key regulator of neurite outgrowth, vesicle trafficking and cancer cell proliferation. CDK16 is activated through binding to cyclin Y via a phosphorylation-d...

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Bibliographic Details
Main Authors: Dixon-Clarke, S, Shehata, S, Krojer, T, Sharpe, T, von Delft, F, Sakamoto, K, Bullock, A
Format: Journal article
Language:English
Published: Portland Press 2017