Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters

<p>Hypoxia inducible factor (HIF) directs an extensive transcripti onal cascade that transduces numerous adaptive responses to hypoxia. Pan-genomic analyses, using chromatin immunoprecipitation and transcript profiling, h ave revealed large numbers of HIF-binding sites that are generally a...

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Bibliographic Details
Main Authors: Platt, J, Salama, R, Smythies, J, Choudhry, H, Davies, J, Hughes, J, Ratcliffe, P, Mole, D
Format: Journal article
Published: EMBO Press 2016