The role of MYB in MLL-AF9 leukaemia

<p>MYB is a DNA-binding transcription factor with a critical role in the establishment of definitive haematopoiesis. In haematological malignancies, MYB is a direct downstream target common to several MLL-fusion proteins (MLL-FP), including MLL-AF9, the most common MLL-FP in acute myeloid leuk...

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Bibliographic Details
Main Author: Lau, IJ
Other Authors: Milne, T
Format: Thesis
Language:English
Published: 2019
Subjects: