Reduced levels of neuraminidase of influenza A viruses correlate with attenuated phenotypes in mice.
We have previously obtained four transfectant influenza A viruses containing neuraminidase (NA) genes with mutated base pairs in the conserved double-stranded RNA region of the viral promoter by using a ribonucleoprotein transfection system. Two mutant viruses (D2 and D1/2) which share a C-G--&g...
Principais autores: | , , , , , |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
2000
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