Matrix metalloproteinase expression in an experimentally-induced DTH model of multiple sclerosis in the rat CNS.

In an experimentally-induced DTH model of MS, we examined mRNA and protein expression of a range of MMPs and of TNFalpha to establish the contribution that individual MMPs might make to the pathogenesis. In control rat brain, mRNA for all of the MMPs examined was detectable. However, by immunohistoc...

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Bibliographic Details
Main Authors: Anthony, D, Miller, K, Fearn, S, Townsend, M, Opdenakker, G, Wells, G, Clements, J, Chandler, S, Gearing, A, Perry, V
Format: Journal article
Language:English
Published: 1998