Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors

During pancreatic development, proliferating pancreatic progenitors activate the proendocrine transcription factor neurogenin 3 (NEUROG3), exit the cell cycle, and differentiate into islet cells. The mechanisms that direct robust NEUROG3 expression within a subset of progenitor cells control the siz...

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Bibliographic Details
Main Authors: Krentz, NAJ, van Hoof, D, Li, Z, Watanabe, A, Tang, M, Nian, C, German, MS, Lynn, FC
Format: Journal article
Language:English
Published: Elsevier 2017