Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors
During pancreatic development, proliferating pancreatic progenitors activate the proendocrine transcription factor neurogenin 3 (NEUROG3), exit the cell cycle, and differentiate into islet cells. The mechanisms that direct robust NEUROG3 expression within a subset of progenitor cells control the siz...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2017
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