Single-cell transcriptome analysis of CD8 + T-cell memory inflation

Background: Persistent viruses such as murine cytomegalovirus (MCMV) and adenovirus-based vaccines induce strong, sustained CD8 + T-cell responses, described as memory "inflation". These retain functionality, home to peripheral organs and are associated with a distinct transcriptional prog...

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Bibliographic Details
Main Authors: Highton, A, Zinser, M, Lee, L, Hutchings, C, De Lara, C, Phetsouphanh, C, Willberg, C, Gordon, C, Klenerman, P, Marchi, E
Format: Journal article
Language:English
Published: F100 Research 2019