Isolation of human monoclonal antibodies by mammalian cell display.

Due to their low immunogenicity in patients, humanized or fully human mAbs are becoming increasingly important for the treatment of a growing number of diseases, including cancer, infections, and immune disorders. Here, we describe a technology allowing for the rapid isolation of fully human mAbs. I...

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Hlavní autoři: Beerli, R, Bauer, M, Buser, R, Gwerder, M, Muntwiler, S, Maurer, P, Saudan, P, Bachmann, M
Médium: Journal article
Jazyk:English
Vydáno: 2008