Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo.

The lack of cell-mediated (Th1-like) immunity that is often associated with strong humoral immune responses is thought to be due in part to the inhibition of Th1 effector function by the Th2-derived cytokine interleukin-10 (IL-10). This hypothesis, however, is based entirely on results from in vitro...

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Bibliographic Details
Main Authors: Powrie, F, Menon, S, Coffman, R
Format: Journal article
Language:English
Published: 1993