Targeting tumour-associated macrophages with locally-expressed T cell engagers
<p>Tumour associated macrophages (TAMs) are implicated in cancer progression but can also exert anti-tumour activities. In this thesis, a strategy to redirect endogenous T cell cytotoxicity towards cancer supporting (M2-like) TAMs is explored. A panel of novel bi- and tri-valent T cell engager...
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| Format: | Thesis |
| Language: | English |
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2020
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