Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes.

Highly active antiretroviral therapy (HAART) has been advocated for the management of primary HIV-1 infection without clear understanding of its immunological effects. Here, we demonstrate that early use of HAART during primary infection preserves HIV-specific CD8(+) T cells physically and functiona...

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Bibliographic Details
Main Authors: Oxenius, A, Price, D, Easterbrook, P, O'Callaghan, C, Kelleher, A, Whelan, J, Sontag, G, Sewell, A, Phillips, R
Format: Journal article
Language:English
Published: 2000