Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health

Mitochondrial supercomplexes form around a conserved core of monomeric complex I and dimeric complex III; wherein a subunit of the former, NDUFA11, is conspicuously situated at the interface. We identified nduf-11 (B0491.5) as encoding the Caenorhabditis elegans homologue of NDUFA11. Animals homozyg...

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Bibliographic Details
Main Authors: Knapp-Wilson, A, Pereira, GC, Buzzard, E, Ford, HC, Richardson, A, Corey, RA, Neal, C, Verkade, P, Halestrap, AP, Gold, VAM, Kuwabara, PE, Collinson, I
Format: Journal article
Language:English
Published: The Company of Biologists 2021