Different pathways of colorectal carcinogenesis and their clinical pictures.
An entertaining debate in cancer genetics concerns the relative importance of selection for a growth advantage and genomic instability in tumorigenesis. Below, I present evidence that shows that selection is more important, particularly in the early stages of tumorigenesis, but that genomic instabil...
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Bibliographic Details
| Main Author: |
Tomlinson, I |
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| Format: | Journal article
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| Language: | English |
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| Published: |
2000
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