Different pathways of colorectal carcinogenesis and their clinical pictures.

An entertaining debate in cancer genetics concerns the relative importance of selection for a growth advantage and genomic instability in tumorigenesis. Below, I present evidence that shows that selection is more important, particularly in the early stages of tumorigenesis, but that genomic instabil...

Полное описание

Библиографические подробности
Главный автор: Tomlinson, I
Формат: Journal article
Язык:English
Опубликовано: 2000