An open-trial evaluation of mitoxantrone in the treatment of progressive MS.

We treated 13 patients with progressive MS with mitoxantrone. All patients received a standard IV dose of mitoxantrone (8 mg/m2) every 3 weeks for a total of seven infusions, with dosage adjustments depending on the hematologic profile at the nadir. The treatment was well tolerated, with the most co...

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Bibliographic Details
Main Authors: Noseworthy, J, Hopkins, M, Vandervoort, M, Karlik, S, Lee, D, Penman, M, Rice, G, Grinwich, K, Cauvier, H, Harris, B
Format: Journal article
Language:English
Published: 1993