Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway.
Structural and biochemical studies of the orf12 gene product (ORF12) from the clavulanic acid (CA) biosynthesis gene cluster are described. Sequence and crystallographic analyses reveal two domains: a C-terminal penicillin-binding protein (PBP)/β-lactamase-type fold with highest structural similarit...
Κύριοι συγγραφείς: | Valegård, K, Iqbal, A, Kershaw, N, Ivison, D, Généreux, C, Dubus, A, Blikstad, C, Demetriades, M, Hopkinson, R, Lloyd, A, Roper, D, Schofield, C, Andersson, I, McDonough, M |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2013
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Clavulanic acid dehydrogenase: structural and biochemical analysis of the final step in the biosynthesis of the beta-lactamase inhibitor clavulanic acid.
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ORF17 from the clavulanic acid biosynthesis gene cluster catalyzes the ATP-dependent formation of N-glycyl-clavaminic acid.
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Crystallographic and mass spectrometric analyses of a tandem GNAT protein from the clavulanic acid biosynthesis pathway.
ανά: Iqbal, A, κ.ά.
Έκδοση: (2010) -
Crystal structures of an oligopeptide-binding protein from the biosynthetic pathway of the beta-lactamase inhibitor clavulanic acid.
ανά: Mackenzie, A, κ.ά.
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Chemistry and biosynthesis of clavulanic acid and other clavams.
ανά: Baggaley, K, κ.ά.
Έκδοση: (1997)