The 5-HT2C receptor agonist meta-chlorophenylpiperazine (mCPP) reduces palatable food consumption and BOLD fMRI responses to food images in healthy female volunteers

Rationale Brain 5-HT2C receptors form part of a neural network that controls eating behaviour. 5-HT2C receptor agonists decrease food intake by activating proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus, but recent research in rodents has suggested that 5-HT2C receptor...

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Bibliographic Details
Main Authors: Thomas, J, Dourish, C, Tomlinson, J, Hassan-Smith, Z, Hansen, P, Higgs, S
Format: Journal article
Language:English
Published: Springer 2017