Oxygen sensing by HIF hydroxylases.
The transcription factor HIF (hypoxia-inducible factor) has a central role in oxygen homeostasis in animals ranging from nematode worms to man. Recent studies have shown that this factor is regulated by an unprecedented signalling mechanism that involves post-translational hydroxylation. This hydrox...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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