Oxygen sensing by HIF hydroxylases.
The transcription factor HIF (hypoxia-inducible factor) has a central role in oxygen homeostasis in animals ranging from nematode worms to man. Recent studies have shown that this factor is regulated by an unprecedented signalling mechanism that involves post-translational hydroxylation. This hydrox...
Huvudupphovsmän: | Schofield, C, Ratcliffe, P |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
2004
|
Liknande verk
-
Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.
av: Kaelin, W, et al.
Publicerad: (2008) -
Signalling hypoxia by HIF hydroxylases.
av: Schofield, C, et al.
Publicerad: (2005) -
Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
av: Webb, J, et al.
Publicerad: (2009) -
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
av: Chowdhury, R, et al.
Publicerad: (2016) -
Regulation of HIF: prolyl hydroxylases.
av: Stolze, I, et al.
Publicerad: (2006)