Local adenoviral expression of Fas ligand upregulates pro-inflammatory immune responses in the CNS.
The central nervous system (CNS) is a site of relative immunological privilege; despite this it can be a target of the immune system under certain conditions. For example, adenoviral vectors elicit an immune response strong enough to result in antigen elimination, in immunologically primed animals....
Main Authors: | , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2004
|