Human-mouse quantitative trait locus concordance and the dissection of a human neuroticism locus.

BACKGROUND: Exploiting synteny between mouse and human disease loci has been proposed as a cost-effective method for the identification of human susceptibility genes. Here we explore its utility in an analysis of a human personality trait, neuroticism, which can be modeled in mice by tests of emoti...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Fullerton, J, Willis-Owen, SA, Yalcin, B, Shifman, S, Copley, R, Miller, SR, Bhomra, A, Davidson, S, Oliver, P, Mott, R, Flint, J
Format: Journal article
Sprache:English
Veröffentlicht: 2008