Interactome rewiring following pharmacological targeting of BET bromodomains
Targeting bromodomains (BRDs) of the bromo-and-extra-terminal (BET) family offers opportunities for therapeutic intervention in cancer and other diseases. Here, we profile the interactomes of BRD2, BRD3, BRD4, and BRDT following treatment with the pan-BET BRD inhibitor JQ1, revealing broad rewiring...
| Үндсэн зохиолчид: | , , , , , , , , , , , , , , , , , , |
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| Формат: | Journal article |
| Хэвлэсэн: |
Elsevier
2018
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