Screening out irrelevant cell-based models of disease

The common and persistent failures to translate promising preclinical drug candidates into clinical success highlight the limited effectiveness of disease models currently used in drug discovery. An apparent reluctance to explore and adopt alternative cell- and tissue-based model systems, coupled wi...

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Bibliographic Details
Main Authors: Horvath, P, Aulner, N, Bickle, M, Davies, A, Nery, E, Ebner, D, Montoya, M, Östling, P, Pietiäinen, V, Price, L, Shorte, S, Turcatti, G, von Schantz, C, Carragher, N
Format: Journal article
Language:English
Published: Nature Publishing Group 2016