Screening out irrelevant cell-based models of disease

The common and persistent failures to translate promising preclinical drug candidates into clinical success highlight the limited effectiveness of disease models currently used in drug discovery. An apparent reluctance to explore and adopt alternative cell- and tissue-based model systems, coupled wi...

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Hlavní autoři: Horvath, P, Aulner, N, Bickle, M, Davies, A, Nery, E, Ebner, D, Montoya, M, Östling, P, Pietiäinen, V, Price, L, Shorte, S, Turcatti, G, von Schantz, C, Carragher, N
Médium: Journal article
Jazyk:English
Vydáno: Nature Publishing Group 2016