Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.

Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.

Chromatin structure is tightly intertwined with transcription regulation. Here we compared the chromosomal architectures of fetal and adult human erythroblasts and found that, globally, chromatin structures and compartments A/B are highly similar at both developmental stages. At a finer scale, we de...

書誌詳細
主要な著者:	Huang, P, Keller, C, Giardine, B, Grevet, J, Davies, J, Hughes, J, Kurita, R, Nakamura, Y, Hardison, R, Blobel, G
フォーマット:	Journal article
言語:	English
出版事項:	Cold Spring Harbour Laboratory Press 2017

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