The induction of a nucleoplasmic reticulum by prelamin A accumulation requires CTP:phosphocholine cytidylyltransferase-α

Farnesylated prelamin A accumulates when the final endoproteolytic maturation of the protein fails to occur and causes a dysmorphic nuclear phenotype; however, the morphology and mechanisms of biogenesis of these changes remain unclear. We show here that acute prelamin A accumulation after reduction...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Goulbourne, C, Malhas, A, Vaux, D
स्वरूप: Journal article
भाषा:English
प्रकाशित: Company of Biologists 2011