Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease.

The identification of the role of genetic variants within NOD2 (CARD15) in Crohn's disease and ulcerative colitis susceptibility highlight the role of the innate immune system in inflammatory bowel disease (IBD) pathogenesis. NOD1 (CARD4) is located on chromosome 7p14.3, in a region of known li...

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Bibliographic Details
Main Authors: McGovern, D, Hysi, P, Ahmad, T, van Heel, D, Moffatt, M, Carey, A, Cookson, W, Jewell, D
Format: Journal article
Language:English
Published: 2005