ASYMMETRIC-SYNTHESIS OF SYN-ALPHA-ALKYL-BETA-AMINO ACIDS

ASYMMETRIC-SYNTHESIS OF SYN-ALPHA-ALKYL-BETA-AMINO ACIDS

An investigation into the reactivity of the highly stereoselective conjugate nucleophile lithium N-benzyl-N-α-methylbenzylamide 1 with α-alkyl-α,β-unsaturated esters has led to the development of a versatile asymmetric synthesis of syn-α-alkyl-β-amino acids. By performing the conjugate additions in...

書誌詳細
主要な著者:	Davies, S, Ichihara, O, Walters, I
フォーマット:	Journal article
出版事項:	1994

類似資料

ASYMMETRIC-SYNTHESIS OF ANTI-ALPHA-ALKYL-BETA-AMINO ACIDS
著者:: Davies, S, 等
出版事項: (1994)

ASYMMETRIC-SYNTHESIS OF ANTI-ALPHA-ALKYL-BETA-AMINO CARBOXAMIDES
著者:: Davies, S, 等
出版事項: (1995)

Asymmetric synthesis of N-protected syn and anti (E)-3-amino-2-hydroxy-4-hexenoate: A practical method for the C-alpha epimerization of anti beta-amino-alpha-hydroxy acids
著者:: Brackenridge, I, 等
出版事項: (1999)

The use of lithium (alpha-methylbenzyl)allylamide for the asymmetric synthesis of unsaturated beta-amino acid derivatives
著者:: Davies, S, 等
出版事項: (1997)

ASYMMETRIC-SYNTHESIS OF R-BETA-AMINO BUTANOIC ACID AND S-BETA-TYROSINE - HOMOCHIRAL LITHIUM AMIDE EQUIVALENTS FOR MICHAEL ADDITIONS TO ALPHA,BETA-UNSATURATED ESTERS
著者:: Davies, S, 等
出版事項: (1991)

Asymmetric synthesis of a highly functionalized beta-amino acid: the key amino acid of sperabillins B and D
著者:: Davies, S, 等
出版事項: (1999)

ASYMMETRIC SYNTHESES OF BETA-PHENYLALANINE, ALPHA-METHYL-BETA-PHENYLALANINES AND DERIVATIVES
著者:: Davies, S, 等
出版事項: (1993)

Asymmetric synthesis of beta-amino acids via the Michael addition of chiral metal amides
著者:: Davies, S, 等
出版事項: (1997)

Asymmetric synthesis of syn- and anti-alpha-deuterio-beta(3)-phenylalanine derivatives
著者:: Davies, S, 等
出版事項: (2011)

Homochiral lithium amides for the asymmetric synthesis of beta-amino acids
著者:: Davies, S, 等
出版事項: (2006)

ASYMMETRIC-SYNTHESIS OF BETA-AMINO-ALPHA-HYDROXY ACIDS VIA DIASTEREOSELECTIVE HYDROXYLATION OF HOMOCHIRAL BETA-AMINO ENOLATES
著者:: Bunnage, M, 等
出版事項: (1994)

Asymmetric synthesis of alpha-amino carbonyls (aldehydes, ketones and acids) using lithium (R)-N-benzyl-N-alpha-methylbenzylamide
著者:: Davies, S, 等
出版事項: (2001)

Asymmetric synthesis of beta-amino acid scaffolds
著者:: Bull, S, 等
出版事項: (2001)

Asymmetric synthesis of beta-fluoroaryl-beta-amino acids
著者:: Davies, S, 等
出版事項: (2012)

Asymmetric synthesis of alpha-mercapto-beta-amino acid derivatives: application to the synthesis of polysubstituted thiomorpholines
著者:: Candela-Lena, J, 等
出版事項: (2006)

ASYMMETRIC-SYNTHESIS OF (-)-(1R,2S)-CISPENTACIN AND RELATED CIS-2-AMINO AND TRANS-2-AMINO CYCLOPENTANE-1-CARBOXYLIC AND CYCLOHEXANE-1-CARBOXYLIC ACIDS
著者:: Davies, S, 等
出版事項: (1994)

ASYMMETRIC-SYNTHESIS OF DIFFERENTIALLY PROTECTED ALPHA-ALKYL SUCCINATES
著者:: Bashiardes, G, 等
出版事項: (1989)

The asymmetric synthesis of beta-haloaryl-beta-amino acid derivatives
著者:: Bull, S, 等
出版事項: (2000)

SuperQuat N-acyl-5,5-dimethyloxazolidin-2-ones for the asymmetric synthesis of alpha-alkyl and beta-alkyl aldehydes.
著者:: Bull, S, 等
出版事項: (2003)

Asymmetric synthesis of beta-pyridyl-beta-amino acid derivatives
著者:: Bull, S, 等
出版事項: (2002)

Asymmetric synthesis of beta-haloaryl beta-amino acid derivatives
著者:: Bull, S, 等
出版事項: (2001)

Trading N and O: asymmetric syntheses of beta-hydroxy-alpha-amino acids via alpha-hydroxy-beta-amino esters
著者:: Davies, S, 等
出版事項: (2013)

Asymmetric synthesis of alpha-amino carbonyl derivatives using lithium (R)-N-benzyl-N-alpha-methylbenzylamide
著者:: Davies, S, 等
出版事項: (2002)

Selective deprotection strategies to N-(alpha-methylbenzyl)-beta-amino esters and derived beta lactams
著者:: Davies, S, 等
出版事項: (1998)

CHIRAL SUCCINATE ENOLATE EQUIVALENTS FOR THE ASYMMETRIC-SYNTHESIS OF ALPHA-ALKYL SUCCINIC ACID-DERIVATIVES
著者:: Bashiardes, G, 等
出版事項: (1989)

Trading N and O. Part 4: Asymmetric synthesis of syn-β-substituted-α-amino acids
著者:: Davies, S, 等
出版事項: (2018)

LITHIUM (ALPHA-METHYLBENZYL)ALLYLAMIDE - A DIFFERENTIALLY PROTECTED CHIRAL AMMONIA EQUIVALENT FOR THE ASYMMETRIC-SYNTHESIS OF BETA-AMINO ACIDS AND BETA-LACTAMS
著者:: Davies, S, 等
出版事項: (1995)

AN ASYMMETRIC-SYNTHESIS OF N-PROTECTED BETA-AMINO ALDEHYDES AND BETA-AMINO KETONES
著者:: Davies, S, 等
出版事項: (1995)

A SUCCINCT ASYMMETRIC-SYNTHESIS OF (2S,3R)-2-METHYL-3-AMINOPENTANOIC ACID HYDROCHLORIDE
著者:: Davies, S, 等
出版事項: (1994)

AN EXPEDITIOUS ASYMMETRIC-SYNTHESIS OF (-)-(1R,2S)-CISPENTACIN
著者:: Davies, S, 等
出版事項: (1993)

THE ASYMMETRIC-SYNTHESIS OF BETA-LACTAMS - STEREOCONTROLLED ASYMMETRIC TANDEM MICHAEL ADDITIONS AND ALKYLATIONS OF ALPHA,BETA-UNSATURATED ACYL LIGANDS BOUND TO THE CHIRAL AUXILIARY [BETA-C5H5)FE(CO)(PPH3)]
著者:: Davies, S, 等
出版事項: (1986)

Asymmetric synthesis of homochiral differentially protected bis-beta-amino acid scaffolds
著者:: Bull, S, 等
出版事項: (2002)

Asymmetric synthesis and applications of beta-amino Weinreb amides: asymmetric synthesis of (S)-coniine.
著者:: Burke, A, 等
出版事項: (2004)

Alkylation and aldol reactions of acyl derivatives of N-1-(1 '-naphthyl)ethyl-O-tert-butylhydroxylamine: asymmetric synthesis of alpha-alkoxy-, alpha-substituted-beta-alkoxy- and alpha,beta-dialkoxyaldehydes
著者:: Chernega, A, 等
出版事項: (2010)

The preparation and alkylation of a butanedione-derived chiral glycine equivalent and its use for the synthesis of alpha-amino acids and alpha,alpha-disubstituted amino acids
著者:: Harding, C, 等
出版事項: (2004)

Asymmetric synthesis of anti-(2S,3S)- and syn-(2R,3S)-diaminobutanoic acid.
著者:: Bunnage, M, 等
出版事項: (2003)

Asymmetric synthesis of 2-alkyl- and 2-aryl-3-aminopropionic acids (beta2-amino acids) from (S)-N-acryloyl-5,5-dimethyloxazolidin-2-one SuperQuat derivatives.
著者:: Beddow, J, 等
出版事項: (2004)

Asymmetric synthesis of (+)-negamycin
著者:: Davies, S, 等
出版事項: (1996)

Aziridines and aziridinium intermediates in the asymmetric synthesis of beta-substituted-alpha-amino acids and 1,2,3,4-tetrahydroisoquinolines
著者:: Frost, A
出版事項: (2015)

Asymmetric synthesis of a homochiral differentially protected pseudo-meso bis-beta-amino acid scaffold
著者:: Bull, S, 等
出版事項: (2001)