Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model

Understanding the host pathways that define susceptibility to Severe-acute-respiratory-syndrome-coronavirus-2 (SARS-CoV-2) infection and disease are essential for the design of new therapies. Oxygen levels in the microenvironment define the transcriptional landscape, however the influence of hypoxia...

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Bibliographic Details
Main Authors: Wing, PAC, Prange-Barczynska, M, Cross, A, Crotta, S, Orbegozo Rubio, C, Cheng, X, Harris, JM, Zhuang, X, Johnson, RL, Ryan, KA, Hall, Y, Carroll, MW, Issa, F, Balfe, P, Wack, A, Bishop, T, Salguero, FJ, McKeating, JA
Format: Journal article
Language:English
Published: Public Library of Science 2022