Tightrope act: Autophagy in stem cell renewal, differentiation, proliferation, and aging
Autophagy is a constitutive lysosomal catabolic pathway that degrades damaged organelles and protein aggregates. Stem cells are characterized by self-renewal, pluripotency, and quiescence; their long life span, limited capacity to dilute cellular waste and spent organelles due to quiescence, along w...
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Format: | Journal article |
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2013
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