a-Amidoaldehydes as substrates in rhodium-catalyzed intermolecular alkyne hydroacylation: The synthesis of a-amidoketones

a-Amidoaldehydes as substrates in rhodium-catalyzed intermolecular alkyne hydroacylation: The synthesis of a-amidoketones

Visa andra versioner (1)

We show that readily available α‐amidoaldehydes are effective substrates for intermolecular Rh‐catalyzed alkyne hydroacylation reactions. The catalyst [Rh(dppe)(C6H5F)][BArF4] provides good reactivity, and allows a broad range of aldehydes and alkynes to be used as substrates, delivering α‐amidoketo...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Pal, R, O'Brien, SC, Willis, MC
Materialtyp:	Journal article
Språk:	English
Publicerad:	Wiley 2020

Liknande verk

α‐Amidoaldehydes as substrates in rhodium‐catalyzed intermolecular alkyne hydroacylation: The synthesis of α‐Amidoketones
av: Pal, R, et al.
Publicerad: (2020)

Traceless chelation-controlled rhodium-catalyzed intermolecular alkene and alkyne hydroacylation.
av: Hooper, J, et al.
Publicerad: (2013)

Rhodium (I) catalyzed intermolecular hydroacylation.
av: Sapmaz, S, et al.
Publicerad: (2001)

Exploiting carbonyl groups to control intermolecular rhodium-catalyzed alkene and alkyne hydroacylation
av: Coxon, TJ, et al.
Publicerad: (2017)

Rhodium-catalyzed intermolecular chelation controlled alkene and alkyne hydroacylation: synthetic scope of beta-S-substituted aldehyde substrates.
av: Willis, M, et al.
Publicerad: (2006)

Rhodium-catalyzed enantioselective intermolecular hydroacylation reactions
av: Gonzalez-Rodriguez, C, et al.
Publicerad: (2011)

O-substituted alkyl aldehydes for rhodium-catalyzed intermolecular alkyne hydroacylation: the utility of methylthiomethyl ethers.
av: Parsons, SR, et al.
Publicerad: (2011)

Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation
av: Moseley, D
Publicerad: (2022)

2-Aminobenzaldehydes as versatile substrates for rhodium-catalyzed alkyne hydroacylation: application to dihydroquinolone synthesis.
av: Castaing, M, et al.
Publicerad: (2013)

An enamine controlling group for rhodium-catalyzed intermolecular hydroacylation
av: Straker, R, et al.
Publicerad: (2018)

Diversely substituted quinolines via rhodium-catalyzed alkyne hydroacylation
av: Willis, M, et al.
Publicerad: (2016)

Rhodium-catalysed intermolecular alkyne hydroacylation: the enantioselective synthesis of α- and β-substituted ketones by kinetic resolution.
av: González-Rodríguez, C, et al.
Publicerad: (2010)

Intermolecular rhodium catalyzed hydroacylation of allenes: the regioselective synthesis of beta,gamma-unsaturated ketones
av: Randell-Sly, H, et al.
Publicerad: (2009)

Rhodium-catalysed linear-selective alkyne hydroacylation.
av: Poingdestre, S, et al.
Publicerad: (2012)

Replacing dichloroethane as a solvent for rhodium-catalysed intermolecular alkyne hydroacylation reactions: the utility of propylene carbonate
av: Lenden, P, et al.
Publicerad: (2011)

Rhodium-catalyzed branched-selective alkyne hydroacylation: a ligand-controlled regioselectivity switch.
av: González-Rodríguez, C, et al.
Publicerad: (2011)

Transition metal catalyzed alkene and alkyne hydroacylation.
av: Willis, M
Publicerad: (2010)

Mechanistic studies of rhodium-catalysed intermolecular hydroacylation
av: Barwick-Silk, J
Publicerad: (2018)

Catalytic enantioselective intermolecular hydroacylation: rhodium-catalyzed combination of beta-S-aldehydes and 1,3-disubstituted allenes.
av: Osborne, J, et al.
Publicerad: (2008)

Controlling selectivity in the rhodium-catalysed intermolecular hydroacylation reaction
av: Pawley, R
Publicerad: (2012)

Azine N-oxides as effective controlling groups for Rh-catalysed intermolecular alkyne hydroacylation
av: Moseley, DF, et al.
Publicerad: (2021)

Chelation-controlled intermolecular alkene and alkyne hydroacylation: the utility of beta-thioacetal aldehydes.
av: Willis, M, et al.
Publicerad: (2005)

Tandem catalytic processes involving Rhodium-catalysed intermolecular hydroacylation
av: Lenden, P
Publicerad: (2011)

Exploring small bite-angle PNP and PCP ligands for the rhodium-catalysed intermolecular hydroacylation of b-s-substituted aldehydes with alkenes and alkynes
av: Pernik, I
Publicerad: (2014)

Hydroacylation of Alkenes, Alkynes, and Allenes
av: Willis, M
Publicerad: (2014)

Exploring Small Bite-Angle Ligands for the Rhodium-Catalyzed Intermolecular Hydroacylation of beta-S-Substituted Aldehydes with 1-Octene and 1-Octyne
av: Pernik, I, et al.
Publicerad: (2012)

Intermolecular hydroacylation: high activity rhodium catalysts containing small-bite-angle diphosphine ligands.
av: Chaplin, AB, et al.
Publicerad: (2012)

Traceless rhodium-catalyzed hydroacylation using alkyl aldehydes: the enantioselective synthesis of β-aryl ketones
av: Willis, M, et al.
Publicerad: (2016)

Intermolecular Alkyne Hydroacylation. Mechanistic Insight from the Isolation of the Vinyl Intermediate That Precedes Reductive Elimination
av: Pawley, R, et al.
Publicerad: (2012)

Enantioselective three-component assembly of β’-aryl-enones using a rhodium-catalyzed alkyne hydroacylation/aryl boronic acid conjugate addition sequence
av: Gao, M, et al.
Publicerad: (2017)

α-amino aldehydes as readily available chiral aldehydes for Rh-catalyzed alkyne hydroacylation
av: Hooper, JF, et al.
Publicerad: (2016)

Ketone synthesis via rhodium-catalyzed traceless chelation-controlled hydroacylation reactions
av: Gao, M
Publicerad: (2018)

Two-component assembly of thiochroman-4-ones and tet-rahydrothiopyran-4-ones using a rhodium-catalyzed alkyne hydroacylation/thio-conjugate-addition sequence
av: Willis, M, et al.
Publicerad: (2016)

An alkyne hydroacylation route to highly substituted furans.
av: Lenden, P, et al.
Publicerad: (2011)

Applications of rhodium-catalysed hydroacylation in heterocycle synthesis
av: Majhail, M
Publicerad: (2016)

Rhodium catalysed hydroacylation reactions in the synthesis of heterocycles
av: Ylioja, P
Publicerad: (2011)

New reactivity and selectivity in rhodium-catalysed hydroacylation
av: Pal, R
Publicerad: (2020)

Exploiting rhodium-catalysed ynamide hydroacylation as a platform for divergent heterocycle synthesis
av: Straker, R, et al.
Publicerad: (2017)

Sequential catalysis: Exploiting a single rhodium(I) catalyst to promote an alkyne hydroacylation–aryl boronic acid conjugate addition sequence
av: Fernández, M, et al.
Publicerad: (2016)

Intermolecular alkene and alkyne hydroacylation with beta-S-substituted aldehydes: mechanistic insight into the role of a hemilabile P-O-P ligand.
av: Moxham, G, et al.
Publicerad: (2008)