Phosphodiesterases maintain signaling fidelity via compartmentalization of cyclic nucleotides.

Novel technological advances have improved our understanding of how cyclic nucleotides are able to convey signals faithfully between cellular compartments. Phosphodiesterases play a crucial role in shaping these signals in health and disease. The concept of compartmentalization is guiding the search...

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Bibliographic Details
Main Authors: Lomas, O, Zaccolo, M
Format: Journal article
Language:English
Published: American Physiological Society 2014