Synthesis and glycosidase inhibition of broussonetine M and its analogues

Cross-metathesis (CM) and Keck asymmetric allylation, which allows access to defined stereochemistry of a remote side chain hydroxyl group, are the key steps in a versatile synthesis of broussonetine M (3) from the d-arabinose-derived cyclic nitrone 14. By a similar strategy, ent-broussonetine M (en...

Полное описание

Библиографические подробности
Главные авторы: Wu, Q, Kinami, K, Kato, A, Li, Y, Fleet, G, Yu, C, Jia, Y
Формат: Journal article
Язык:English
Опубликовано: MDPI 2019