Synthesis and glycosidase inhibition of broussonetine M and its analogues

Cross-metathesis (CM) and Keck asymmetric allylation, which allows access to defined stereochemistry of a remote side chain hydroxyl group, are the key steps in a versatile synthesis of broussonetine M (3) from the d-arabinose-derived cyclic nitrone 14. By a similar strategy, ent-broussonetine M (en...

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Bibliographic Details
Main Authors: Wu, Q, Kinami, K, Kato, A, Li, Y, Fleet, G, Yu, C, Jia, Y
Format: Journal article
Language:English
Published: MDPI 2019