Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo.

Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo.

BACKGROUND: The cationic lipid Genzyme lipid (GL) 67 is the current "gold-standard" for in vivo lung gene transfer. Here, we assessed, if GL67 mediated uptake of siRNAs and asODNs into airway epithelium in vivo. METHODS: Anti-lacZ and ENaC (epithelial sodium channel) siRNA and asODN were...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Griesenbach, U, Kitson, C, Escudero Garcia, S, Farley, R, Singh, C, Somerton, L, Painter, H, Smith, R, Gill, DR, Hyde, S, Chow, Y, Hu, J, Gray, M, Edbrooke, M, Ogilvie, V, MacGregor, G, Scheule, R, Cheng, S, Caplen, N, Alton, E
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2006

অনুরূপ উপাদানগুলি

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