Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis.

Tumour necrosis factor alpha (TNF alpha) is a critical inflammatory mediator in rheumatoid arthritis, and may therefore be a useful target for specific immunotherapy. In support of this hypothesis, we previously observed beneficial responses in patients with active rheumatoid arthritis after open-la...

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Bibliographic Details
Main Authors: Elliott, M, Maini, R, Feldmann, M, Kalden, JR, Antoni, C, Smolen, J, Leeb, B, Breedveld, F, Macfarlane, J, Bijl, H
Format: Journal article
Language:English
Published: 1994