Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases
Treatment options for Ankylosing Spondylitis (AS) are still limited. The T helper cell 17 (Th17) pathway has emerged as a major driver of disease pathogenesis and a good treatment target. Janus kinases (JAK) are key transducers of cytokine signals in Th17 cells and therefore promising targets for th...
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Springer Nature
2018
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