Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.

Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.

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Nitric oxide, generated by the nitric oxide synthase (NOS) enzymes, plays pivotal roles in cardiovascular homeostasis and in the pathogenesis of cardiovascular disease. The NOS cofactor, tetrahydrobiopterin (BH4), is an important regulator of NOS function, since BH4 is required to maintain enzymatic...

書目詳細資料
Main Authors:	Crabtree, M, Channon, K
格式:	Journal article
語言:	English
出版:	2011

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