Diffusive spatio-temporal noise in a first-passage time model for intracellular calcium release

The intracellular release of calcium from the endoplasmic reticulum is controlled by ion channels. The resulting calcium signals exhibit a rich spatio-temporal signature, which originates at least partly from microscopic fluctuations. While stochasticity in the gating transition of ion channels has...

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Bibliographic Details
Main Authors: Flegg, M, Rudiger, S, Erban, R
Format: Journal article
Published: 2013