Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency.

Autosomal recessive interleukin-1 receptor-associated kinase (IRAK)-4 and myeloid differentiation factor (MyD)88 deficiencies impair Toll-like receptor (TLR)- and interleukin-1 receptor-mediated immunity. We documented the clinical features and outcome of 48 patients with IRAK-4 deficiency and 12 pa...

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Bibliographic Details
Main Authors: Picard, C, von Bernuth, H, Ghandil, P, Chrabieh, M, Levy, O, Arkwright, P, McDonald, D, Geha, R, Takada, H, Krause, J, Creech, C, Ku, C, Ehl, S, Maródi, L, Al-Muhsen, S, Al-Hajjar, S, Al-Ghonaium, A, Day-Good, N, Holland, S, Gallin, J, Chapel, H, Speert, D, Rodriguez-Gallego, C, Colino, E, Garty, B
Format: Journal article
Language:English
Published: 2010