The influence of the CTIP Polymorphism, Q418P, on Homologous Recombination and Predisposition to Radiation-Induced Tumorigenesis (mainly rAML) in Mice

Exposure to ionizing radiation increases the incidence of acute myeloid leukemia (AML), which has been diagnosed in Japanese atomic bombing survivors, as well as patients treated with radiotherapy. The genetic basis for susceptibility to radiation-induced AML is not well characterized. We previously...

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Autori principali: Patel, A, Anderson, J, Kraft, D, Finnon, R, Scudamore, C, Manning, G, Bulman, R, Brown, N, Bouffler, S, O'Neill, P, Badie, C
Natura: Journal article
Pubblicazione: Radiation Research Society 2016